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Grants due in December 2027

8 open grants close in December 2027, 7 of them open to small businesses. Every listing links to its official source.

December 2027

Friday, December 3 2 deadlines

Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Dec 3, 2027
Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Dec 3, 2027

Thursday, December 23 5 deadlines

Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Dec 23, 2027
Catalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed)

Department of Health and Human Services Up to $350K Small businesses eligible

Closes Dec 23, 2027
Catalyze: Product Definition for Small Molecules, Biologics and Combination Products - Target Identification and Validation, and Preliminary Product/Lead Series Identification (R61/R33 Clinical Trials Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Dec 23, 2027
Catalyze: Product Definition for Small Molecules, Biologics, and Combination Products - Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Dec 23, 2027
Catalyze: Product Definition Medical Device Prototype Optimization (R33 - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Dec 23, 2027

Friday, December 31 1 deadline

NPS Cooperative Ecosystems Studies Units (CESU) Master Cooperative Agreements

Department of the Interior Others (see eligibility details)

Closes Dec 31, 2027