Oral Diseases and Disorders Research (93.121)

National Institutes of Health

Opened 11 times since 2025. Usually posted in January and June, with deadlines in May.

Based on 11 recorded past opportunities. Opportunities under one Assistance Listing may cover different projects or funding cycles.

When might the next round open?

Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional): expected to open November 5, 2026, according to the current forecast.
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional): expected to open November 5, 2026, according to the current forecast.
Investigator-Focused Award (Parent R35): expected to open May 27, 2027, according to the current forecast.

Open now

Forecast opportunities are expected but are not accepting applications yet.

HEAL Initiative: Whole Joint Health Program (R61/R33 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes in 6 days
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $350K Small businesses eligible

Closes in 13 days
Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)

Department of Health and Human Services Up to $50K Small businesses eligible

Closes in 23 days
Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)

Department of Health and Human Services Up to $200K Small businesses eligible

Closes in 24 days
Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes in 25 days
HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

Department of Health and Human Services Up to $375K Others (see eligibility details)

Closes in 30 days
Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32)

Department of Health and Human Services Small businesses eligible

Closes Dec 2
Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Others (see eligibility details)

Closes Dec 3
NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Dec 4
Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Jan 5, 2027
Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Expected around Jan 5, 2027
Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2027
HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)

Department of Health and Human Services Up to $350K Small businesses eligible

Closes Jan 15, 2027
Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)

Department of Health and Human Services Up to $500K Nonprofits eligible

Closes Jan 27, 2027
NLM Institutional Grants for Research Training in Biomedical Informatics, Data Science, and AI (T15 Independent Clinical Trial Not Allowed)

Department of Health and Human Services $500K to $775K Small businesses eligible

Closes Feb 11, 2027
NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 5, 2027
NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 5, 2027
Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)

Department of Health and Human Services Up to $200K Small businesses eligible

Closes Apr 9, 2027
Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2027
Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 8, 2027
Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes May 8, 2027
Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jun 2, 2027
Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jun 2, 2027
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jul 12, 2027
Successor-in-Interest (Type 6 Parent Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jul 17, 2027
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Aug 18, 2027
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Sep 7, 2027
Investigator-Focused Award (Parent R35)

Department of Health and Human Services Small businesses eligible

Expected around Oct 4, 2027
Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)

Department of Health and Human Services Up to $650K Public and state-controlled colleges

Closes Oct 19, 2027
Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $100K Small businesses eligible

Closes Nov 16, 2027
Continuation or Revision of NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UH3 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Jan 6, 2028
NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Jan 6, 2028
NIDCR Drug, Biologic, Device and/or Procedure Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Jan 6, 2028
Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $375K Others (see eligibility details)

Closes Jan 7, 2028
Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)

Department of Health and Human Services Up to $499K Small businesses eligible

Closes Jan 7, 2028
Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $375K Public and state-controlled colleges

Closes Jan 7, 2028
Screening and Functional Validation of Genomic Variants Associated with Human Congenital Anomalies (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jan 7, 2028
Blueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jan 28, 2028
Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Feb 17, 2028
Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)

Department of Health and Human Services Small businesses eligible

Closes May 4, 2028
NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2028
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2028
INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $200K Small businesses eligible

Closes Jun 15, 2028
INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Jun 15, 2028
Lasker Clinical Research Scholar's Program (Si2/R00 Clinical Trial Optional)

Department of Health and Human Services Up to $499K Small businesses eligible

Closes Jul 7, 2028
Grants for Early Medical/Surgical Specialists' Transition to Aging Research (GEMSSTAR) (R03 Clinical Trial Optional)

Department of Health and Human Services Up to $125K Small businesses eligible

Closes Jul 16, 2028
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Aug 25, 2028
Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $100K Private colleges and universities

Closes Sep 7, 2028
Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed)

Department of Health and Human Services Up to $125K Public and state-controlled colleges

Closes Sep 7, 2028
Community-Based Participatory Research to Advance Data and Practice Transformation (ADAPT) for Optimizing Oral Health for All (UG3/UH3 Clinical Trial Optional)

Department of Health and Human Services Up to $300K Small businesses eligible

Closes Nov 16, 2028
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Nov 30, 2028
Limited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)

Department of Health and Human Services $25K to $250K Small businesses eligible

Closes Jan 26, 2029
SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Apr 5, 2029
Predoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Apr 8, 2029
NIH Brain Development Cohorts (NBDC) and Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Apr 17, 2029
NIH Research Education Program - Research Experiences (Parent R25 - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 5, 2029
NIH Research Educational Program - Mentoring Activities & Networks (Parent R25/UE5 - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 5, 2029
NIH Collaborative International Research Project (Parent PF5 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes May 7, 2029
Centers for AIDS Research (CFAR) and Developmental Centers for AIDS Research (D-CFAR) (P30 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 25, 2029
NIH Research Education Program - Courses, Curriculum & Methods (Parent R25 - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 25, 2029
NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes May 25, 2029
Implementation Science to Advance HIV Prevention, Treatment, and Care (R61/R33 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Jun 20, 2029
Causal Hypotheses on the Oral-Systemic Health Impacts of Human Behaviors among People with Chronic Conditions (U01 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Jul 5, 2029
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)

Department of Health and Human Services Up to $500K Small businesses eligible

Closes Jul 5, 2029
Academic Career Excellence (ACE) Award (K32 Independent Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Jul 12, 2029
Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed)

Department of Health and Human Services Nonprofits eligible

Closes Jul 12, 2029
Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2027, 2028, and 2029 (P50 Clinical Trial Required)

Department of Health and Human Services Small businesses eligible

Closes Sep 25, 2029
Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional)

Department of Health and Human Services Small businesses eligible

Closes Sep 26, 2029
NextTech: Translational Development of Next-Generation Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)

Department of Health and Human Services Small businesses eligible

Closes Dec 1, 2030

Past rounds

HEAL Initiative: Limited Competition for the HEALthy Brain and Child Development (HBCD) Study – Consortium Administrative Core and Data Coordinating Center (U24 Clinical Trial Not Allowed)

RFA-DA-27-014

Posted
June 10, 2026

Deadline
July 10, 2026

Award
Not listed
HEAL Initiative: Limited Competition for the HEALthy Brain and Child Development Study - Research Project Sites (Collaborative U01- Clinical Trial Not Allowed)

RFA-DA-27-013

Posted
June 10, 2026

Deadline
July 10, 2026

Award
Not listed
HEAL INITIATIVE: INTERACT Data Coordination and Integration Center (U24 Clinical Trial Not Allowed)

RFA-AR-27-002

Posted
May 19, 2026

Deadline
October 1, 2026

Award
Not listed
Accelerating Product Excellence in Innovation and for Clinical Adoption (APEx) (U24 Clinical Trial Not Allowed)

RFA-DE-27-002

Posted
May 4, 2026

Deadline
July 10, 2026

Award
Up to $4M
Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)

RFA-DE-27-001

Posted
April 27, 2026

Deadline
October 19, 2026

Award
Not listed
NIH Blueprint for Neuroscience: Coordination Center for Interoception Research (BPCCIR) (U24, Clinical Trial Not Allowed)

RFA-AT-25-004

Posted
September 2, 2025

Deadline
November 10, 2025

Award
Not listed
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)

PAR-25-323

Posted
August 25, 2025

Deadline
May 24, 2026

Award
Not listed
Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)

PAR-25-438

Posted
June 5, 2025

Deadline
December 9, 2025

Award
Up to $1M
Leadership and Coordination Center (LACC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)

RFA-HL-26-011

Posted
January 16, 2025

Deadline
May 2, 2025

Award
Up to $2,000
Limited Competition: Data Analysis and Sharing Center (DASC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)

RFA-HL-26-010

Posted
January 16, 2025

Deadline
May 2, 2025

Award
Up to $2M
Limited Competition: Clinical Research Sites (CRS) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trial Not Allowed)

RFA-HL-26-009

Posted
January 16, 2025

Deadline
May 2, 2025

Award
Up to $2.4M

History from Grants.gov, checked October 24, 2026 at 10:18 AM CT.

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