Government grants for small business

787 grants for small businesses from government funders are open right now. The next deadline is Monday, Oct 26. 293 grants are coming up.

These federal, state and local grants list small businesses among eligible applicants. Check the project, location and operating-history requirements.

Due in July 2027

Apply by Jul 17, 2027

Successor-in-Interest (Type 6 Parent Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open

Due in August 2027

Apply by Aug 11, 2027

Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $150K
Open
Apply by Aug 18, 2027

Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open

Due in September 2027

Apply by Sep 7, 2027

Advancement and Innovation in Measurement of Language Development and Predictors (R01 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 7, 2027

Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 7, 2027

Bioengineering Partnerships with Industry (U01 Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 7, 2027

Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 7, 2027

NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 10, 2027

Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 15, 2027

Michigan State Trade Expansion Program (MI-STEP)

Michigan Economic Development Corporation (with U.S. SBA STEP funding)

Applicants: Small businesses

Michigan

Up to $15K
Open
Apply by Sep 18, 2027

Department of Defense HIV/AIDS Prevention Program

Department of Defense

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 20, 2027

Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and Mathematical Sciences

U.S. National Science Foundation

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

$1 to $1.2M
Open
Apply by Sep 25, 2027

NICHD Resource Program Grants in Bioinformatics (P41 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 28, 2027

Clinical and Translational Science Award (UM1 Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 29, 2027

Research Experiences and/or Mentoring Networks through Research Education to Enhance Clinician-Scientists' Participation in NIDCDs Research (R25 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $250K
Open
Apply by Sep 30, 2027

CHEERS Open Period 1 - All Technical Areas

Department of Defense

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 30, 2027

CHEERS Open Period 2 - All Technical Areas

Department of Defense

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 30, 2027

DOD Defense Health Agency (DHA) Research & Development FY23-FY27 BROAD AGENCY ANNOUNCEMENT for Extramural Medical Research

Department of Defense

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Sep 30, 2027

FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program

Department of Energy - Office of Science

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

$5,000 to $10M
Open

Due in October 2027

Apply by Oct 1, 2027

Home Study and Post-Release Services for Unaccompanied Alien Children

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

$1M to $100M
Open

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Government grants for small business

Due in July 2027

Successor-in-Interest (Type 6 Parent Clinical Trial Optional)

Due in August 2027

Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)

Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

Due in September 2027

Advancement and Innovation in Measurement of Language Development and Predictors (R01 Clinical Trial Not Allowed)

Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed)

Bioengineering Partnerships with Industry (U01 Clinical Trial Optional)

Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)

NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)

Integrating Biospecimen Science Approaches into Clinical Assay Development (U01 Clinical Trial Not Allowed)

Michigan State Trade Expansion Program (MI-STEP)

Department of Defense HIV/AIDS Prevention Program

Joint DMS/NIGMS Initiative to Support Research at the Interface of the Biological and Mathematical Sciences

NICHD Resource Program Grants in Bioinformatics (P41 Clinical Trial Not Allowed)

Clinical and Translational Science Award (UM1 Clinical Trial Optional)

Research Experiences and/or Mentoring Networks through Research Education to Enhance Clinician-Scientists' Participation in NIDCDs Research (R25 Clinical Trial Not Allowed)

CHEERS Open Period 1 - All Technical Areas

CHEERS Open Period 2 - All Technical Areas

DOD Defense Health Agency (DHA) Research & Development FY23-FY27 BROAD AGENCY ANNOUNCEMENT for Extramural Medical Research

FY 2027 Continuation of Solicitation for the Office of Science Financial Assistance Program

Due in October 2027

Home Study and Post-Release Services for Unaccompanied Alien Children

Grant deadline reminders

Reminders for All grant deadlines