Government grants for small business

787 grants for small businesses from government funders are open right now. The next deadline is Monday, Oct 26. 293 grants are coming up.

These federal, state and local grants list small businesses among eligible applicants. Check the project, location and operating-history requirements.

Due in January 2028

Apply by Jan 7, 2028

The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Jan 7, 2028

Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Jan 7, 2028

Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $200K
Open
Apply by Jan 10, 2028

Stimulating Access to Research in Residency (StARR) (R38 Independent Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Jan 28, 2028

Blueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Jan 31, 2028

Commercial Fishing Occupational Safety Research Cooperative Agreement (U01)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

$150K to $975K
Open
Apply by Jan 31, 2028

Commercial Fishing Occupational Safety Training Project Grants (T03)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

$250K to $975K
Open

Due in February 2028

Apply by Feb 17, 2028

Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open

Due in March 2028

Apply by Mar 1, 2028

Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Access (X01 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open

Due in May 2028

Apply by May 1, 2028

2026 Alaska Marine Education and Training Mini-Grant Program

Department of Commerce

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Alaska

$15K to $75K
Open
Apply by May 4, 2028

Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by May 7, 2028

Community-Partnered Nursing Research Centers (P20 Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $500K
Open
Apply by May 7, 2028

NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by May 7, 2028

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Nonprofits, Small businesses

Nationwide

Open
Apply by May 7, 2028

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Nonprofits, Small businesses

Nationwide

Open
Apply by May 7, 2028

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Nonprofits, Small businesses

Nationwide

Open
Apply by May 7, 2028

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Nonprofits, Small businesses

Nationwide

Open
Apply by May 7, 2028

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Nonprofits, Small businesses

Nationwide

Open
Apply by May 7, 2028

Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grant (Parent T35)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by May 7, 2028

Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $1M
Open

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Government grants for small business

Due in January 2028

The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional)

Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R01 Clinical Trial Optional)

Utilizing Invasive Recording and Stimulating Opportunities in Humans to Advance Neural Circuitry Understanding of Mental Health Disorders (R21 Clinical Trial Optional)

Stimulating Access to Research in Residency (StARR) (R38 Independent Clinical Trial Not Allowed)

Blueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional)

Commercial Fishing Occupational Safety Research Cooperative Agreement (U01)

Commercial Fishing Occupational Safety Training Project Grants (T03)

Due in February 2028

Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)

Due in March 2028

Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Access (X01 Clinical Trial Not Allowed)

Due in May 2028

2026 Alaska Marine Education and Training Mini-Grant Program

Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)

Community-Partnered Nursing Research Centers (P20 Clinical Trial Optional)

NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)

Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grant (Parent T35)

Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)

Grant deadline reminders

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