Government grants for small business
20 opportunities are coming up. Applications aren’t open yet.
Open now (783) and all upcoming opportunities
These federal, state and local grants list small businesses among eligible applicants. Check the project, location and operating-history requirements.
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Amount not listed
Coming up
Applications aren’t open yet. Check each grant for announced or estimated dates.
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Expected opening Dec 16, 2026
Innovative Research to Improve Native Hawaiian and Pacific Islander (NHPI) Health Outcomes (R34 - Clinical Trial Optional)
Department of Health and Human Services
Agency forecast; applications are not open yet.
Amount not listed
Coming up -
Expected opening Nov 16, 2026
Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)
Department of Health and Human Services
Agency forecast; applications are not open yet.
Amount not listed
Coming up -
Expected opening Dec 16, 2026
NIOSH Exploratory/Developmental Grant Program (R21)
Department of Health and Human Services
Agency forecast; applications are not open yet.
Up to $300K
Coming up -
Expected opening Dec 17, 2026
NIOSH Small Research Grant Program (R03)
Department of Health and Human Services
Agency forecast; applications are not open yet.
Up to $100K
Coming up -
Expected opening Nov 2, 2026
Research on the Ethical, Legal and Social Implications (ELSI) of Genomics
Department of Health and Human Services
Agency forecast; applications are not open yet.
Amount not listed
Coming up -
Expected opening Dec 20, 2026
The National Network of STI Prevention Training Centers (NNPTC)
Department of Health and Human Services
Agency forecast; applications are not open yet.
$350,000 to $1,000,000
Coming up -
Expected opening Nov 24, 2026
NIH Pragmatic Trials Conducted in Health Care Systems
Department of Health and Human Services
Agency forecast; applications are not open yet.
Amount not listed
Coming up -
Expected opening Nov 17, 2026
The Home Visiting Research, Improvement, Sustainability and Evaluation Center (HV-RISE)
Department of Health and Human Services
Agency forecast; applications are not open yet.
Up to $5M
Coming up -
Expected opening Nov 24, 2026
World Trade Center Youth Research Coordinating Center (U54)
Department of Health and Human Services
Agency forecast; applications are not open yet.
Up to $10M
Coming up -
Expected opening Nov 16, 2026
NIOSH Centers of Excellence for Total Worker Health® (U19)
Department of Health and Human Services
Agency forecast; applications are not open yet.
$500,000 to $1,400,000
Coming up -
Expected opening Jan 1, 2027
Bridge2AI Network for AI Health Science
Department of Health and Human Services
Agency forecast; applications are not open yet.
$1,000,000 to $7,000,000
Coming up -
Expected opening Nov 3, 2026
Collaborative Centers in Children’s Environmental Health Research and Translation (P2C Clinical Trial Optional)
Department of Health and Human Services
Agency forecast; applications are not open yet.
$500,000 to $750,000
Coming up -
Expected opening Dec 4, 2026
NIOSH Centers for Agriculture, Forestry, and Fishing Safety and Health (U54)
Department of Health and Human Services
Agency forecast; applications are not open yet.
Up to $2.2M
Coming up -
Expected opening Dec 4, 2026
NIOSH National Center of Excellence for the Prevention of Childhood Agricultural Injury (U54)
Department of Health and Human Services
Agency forecast; applications are not open yet.
Up to $1.6M
Coming up -
Expected deadline Mar 4, 2027
Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases
Department of Health and Human Services
Agency forecast; applications are not open yet.
$300,000 to $600,000
Coming up -
Expected opening Jan 4, 2027
Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Coordinating Center (CCC) and Data Coordinating Center (DCC)
Department of Health and Human Services
Agency forecast; applications are not open yet.
Amount not listed
Coming up -
Expected opening Jan 4, 2027
Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) Infrastructure – Clinical Enrollment Hubs
Department of Health and Human Services
Agency forecast; applications are not open yet.
Amount not listed
Coming up -
Expected opening Jan 7, 2027
Core State Injury Prevention Program (Core SIPP)
Department of Health and Human Services
Agency forecast; applications are not open yet.
Amount not listed
Coming up -
Expected opening Jan 5, 2027
Promoting Cancer Surveillance Workforce, Education, and Data Use
Department of Health and Human Services
Agency forecast; applications are not open yet.
Amount not listed
Coming up -
Expected opening Jan 11, 2027
Rural Communities Opioid Response Program - Overdose Response
Department of Health and Human Services
Agency forecast; applications are not open yet.
Up to $300K
Coming up