Government grants for small business

787 grants for small businesses from government funders are open right now. The next deadline is Monday, Oct 26. 293 grants are coming up.

These federal, state and local grants list small businesses among eligible applicants. Check the project, location and operating-history requirements.

Due in January 2027

Apply by Jan 26, 2027

National Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Jan 27, 2027

Diabetes Research Centers (P30 Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $1M
Open
Apply by Jan 27, 2027

Specialized Alcohol Research Centers (P50 Clinical trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $1.1M
Open
Apply by Jan 28, 2027

BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $750K
Open
Apply by Jan 28, 2027

Clark County District B Commercial Revitalization and Beautification Grant

Clark County District B (administered by Grow America)

Applicants: Small businesses

Las Vegas, NV

Up to $11K
Open
Apply by Jan 28, 2027

Translational Neural Devices (R61/R33 - Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Jan 29, 2027

Immune Tolerance Network (UM1 Clinical Trial Required)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Jan 29, 2027

Minor Use Minor Species Development of Drugs (R01)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $250K
Open
Apply by Jan 29, 2027

Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Jan 31, 2027

Agriculture Innovation Center Grant Program

Department of Agriculture

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

$600K to $1M
Open
Apply by Jan 31, 2027

Wisconsin Focus on Energy Agribusiness Rebates

Wisconsin Public Service Commission / Focus on Energy

Applicants: Small businesses

Wisconsin

Open

Due in February 2027

Apply by Feb 1, 2027

Cognitive Neuroscience (CogNeuro)

U.S. National Science Foundation

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Feb 2, 2027

Mathematical Sciences Infrastructure Program

U.S. National Science Foundation

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Feb 3, 2027

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $1.5M
Open
Apply by Feb 3, 2027

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Feb 8, 2027

BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Feb 8, 2027

Neural Ensembles & Used Substances (NExUS) Collaboratory: Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances (U01 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Feb 9, 2027

A Science of Science Approach to Analyzing and Innovating the Biomedical Research Enterprise (SoS:BIO)

U.S. National Science Foundation

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

$100K to $250K
Open
Apply by Feb 9, 2027

Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $700K
Open
Apply by Feb 10, 2027

Science of Learning and Augmented Intelligence (SL)

U.S. National Science Foundation

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

From $550
Open

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Government grants for small business

Due in January 2027

National Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed)

Diabetes Research Centers (P30 Clinical Trial Optional)

Specialized Alcohol Research Centers (P50 Clinical trial Optional)

BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)

Clark County District B Commercial Revitalization and Beautification Grant

Translational Neural Devices (R61/R33 - Clinical Trial Optional)

Immune Tolerance Network (UM1 Clinical Trial Required)

Minor Use Minor Species Development of Drugs (R01)

Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)

Agriculture Innovation Center Grant Program

Wisconsin Focus on Energy Agribusiness Rebates

Due in February 2027

Cognitive Neuroscience (CogNeuro)

Mathematical Sciences Infrastructure Program

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)

Neural Ensembles & Used Substances (NExUS) Collaboratory: Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances (U01 Clinical Trial Not Allowed)

A Science of Science Approach to Analyzing and Innovating the Biomedical Research Enterprise (SoS:BIO)

Carcinogen Hazard Assessment Monographs Program (CHAMP) (R01 Clinical Trial Not Allowed)

Science of Learning and Augmented Intelligence (SL)

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