Government grants for small business

787 grants for small businesses from government funders are open right now. The next deadline is Monday, Oct 26. 293 grants are coming up.

These federal, state and local grants list small businesses among eligible applicants. Check the project, location and operating-history requirements.

Due in March 2027

Apply by Mar 19, 2027

Small Business Advantage Grant

Pennsylvania Department of Environmental Protection

Applicants: Small businesses

Pennsylvania

Up to $12K
Open

Due in April 2027

Apply by Apr 1, 2027

Alameda Facade Grant Program

City of Alameda

Applicants: Small businesses

San Francisco, CA

Up to $20K
Open
Apply by Apr 5, 2027

NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)

Department of Health and Human Services

Applicants: For-profit companies, Small businesses

Nationwide

Open
Apply by Apr 5, 2027

NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

Department of Health and Human Services

Applicants: For-profit companies, Small businesses

Nationwide

Open
Apply by Apr 9, 2027

Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $200K
Open
Apply by Apr 15, 2027

Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Up to $250K
Open
Apply by Apr 18, 2027

Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Apr 20, 2027

Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Apr 26, 2027

Notice of Intent to Issue NOFO DE-FOA-0003649: Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels and Feedstocks

Department of Energy

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Apr 28, 2027

NHLBI Emerging Investigator Award (EIA) (R35 Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Apr 28, 2027

NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by Apr 30, 2027

F26AS00105 National Fish Passage Program

Department of the Interior

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

$1 to $1M
Open
Apply by Apr 30, 2027

LPS Qubit Collaboratory (LQC)

Department of Defense

Applicants: Schools and colleges, For-profit companies, Individuals, Local governments, Nonprofits, Small businesses

Nationwide

Open

Due in May 2027

Apply by May 7, 2027

Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by May 7, 2027

Independent Scientist Award (Parent K02 - Independent Clinical Trial Required)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by May 7, 2027

Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by May 7, 2027

Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by May 7, 2027

Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by May 7, 2027

Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open
Apply by May 7, 2027

Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)

Department of Health and Human Services

Applicants: Schools and colleges, For-profit companies, Local governments, Nonprofits, Small businesses, State governments, Tribal governments and organizations

Nationwide

Open

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Government grants for small business

Due in March 2027

Small Business Advantage Grant

Due in April 2027

Alameda Facade Grant Program

NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)

NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)

Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)

Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)

Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)

Notice of Intent to Issue NOFO DE-FOA-0003649: Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels and Feedstocks

NHLBI Emerging Investigator Award (EIA) (R35 Clinical Trial Optional)

NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)

F26AS00105 National Fish Passage Program

LPS Qubit Collaboratory (LQC)

Due in May 2027

Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)

Independent Scientist Award (Parent K02 - Independent Clinical Trial Required)

Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)

Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)

Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required)

Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)

Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)

Grant deadline reminders

Reminders for All grant deadlines